#  Self-Assembly 

 



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 ssDNA-ssDNA pairing, dsDNA-dsDNA pairing, and RecA family protein mediated homologous recombination all involve self-assembly because free energetically favorable interactions form structures from less complex parts.

  [self\_assembly\_1.png](/file_url/116)

 <https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1005421>

 Efraim Feinstein’s PhD thesis considered several self-assembling systems, including the folding of a string of charged beads.

 ![self_assembly_2.png](/sites/g/files/omnuum7031/files/prentiss/files/self_assembly_2.png)

 

 Single molecule measurements of the adhesion of uropathogenic Escherichia coli to mannose also revealed useful strategies for optimizing self-assembly. <https://pubmed.ncbi.nlm.nih.gov/11078520/>, as did studies of the folding of strings of charged beads. The work on the uropathogenic bacteria and the charged beads were done in collaboration with the Whitesides group.



 

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 Attachments- [  image  self\_assembly\_1.png ](/sites/g/files/omnuum7031/files/prentiss/files/self_assembly_1.png)
- [  image  self\_assembly\_2.png ](/sites/g/files/omnuum7031/files/prentiss/files/self_assembly_2.png)
 
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